Make structure a standard layer of liquid biopsy.
We preserve the physical context that conventional blood measurements leave behind, so researchers can study circulating biology as intact spatial objects.
NEBULUM TECHNOLOGIES · SPATIAL BIOLOGY FOR BLOOD
Transforming human health through a deeper view into blood.
Nebulum is building structure-resolved liquid biopsy: preserving fragile circulating biology and turning three-dimensional architecture, molecular composition and cell interactions into measurable research endpoints.
EXTRACELLULAR DNA TRAPCELL NUCLEI (DAPI)WHOLE-BLOOD MATRIX
WHOLE BLOODSTRUCTURE PRESERVEDQUANTITATIVE 3D DATA
MISSION & VISION
See disease biology—and how it changes—through blood.
We envision a future where treatment development is informed not only by what is present in blood, but by how biological structures are organized and interacting.
OUR FOUNDATION
Volumetric imaging and tissue-clearing expertise, translated from solid tissue into liquid biopsy.
WHAT THE PLATFORM CAN DO
Preserve the biology.
Measure the structure.
One connected workflow carries a whole-blood sample from structure-preserving collection to registered volumetric data.
Preserve
Stabilize fragile extracellular structures close to collection and retain them through whole-blood processing.
See in 3D
Embed the retained specimen in an optically matched matrix and image the complete volume through depth.
Interrogate
Resolve morphology, molecular localization and cell–trap relationships within registered events.
Quantify
Convert preserved structures into burden, phenotype and longitudinal research endpoints.
APPLICATIONS
One platform.
Multiple disease questions.
Extracellular DNA traps are implicated across immune escape, autoimmunity, thrombosis and dysregulated inflammation. Nebulum provides a shared spatial measurement language across these fields.
Cancer & immunotherapy
Explore trap burden, checkpoint-marker localization and immune-cell interactions in treatment studies.
Autoimmune disease
Study structural persistence, molecular composition and remodeling across immunomodulatory treatment.
Immunothrombosis & inflammation
Characterize extracellular scaffolds in relation to coagulation, vascular injury and host defense.
TRANSLATIONAL COLLABORATIONBring us the biological question.
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