PRESERVE
Stabilize labile structures at collection.
THE PLATFORMFrom liquid biopsy to
From liquid biopsy to
structure-resolved 3D data.
Nebulum preserves fragile circulating objects from whole blood, immobilizes them in an optically matched matrix and converts the complete volume into population- and event-level research endpoints.
01 / FROM BLOOD TO MATRIX
From liquid biopsy to a
structure-preserving 3D matrix.
Stabilize fragile circulating structures, concentrate the retained specimen and embed it in an optically matched matrix for complete volumetric measurement.
CONCENTRATE + EMBED
Retain rare objects in a thin 3D matrix.
IMAGE
Acquire the complete volume through depth.
ANALYZE + QUANTIFY
Segment objects and compute burden, morphology and spatial endpoints.
ONE SAMPLEPopulation context, without losing event-level spatial structureONE REGISTERED MATRIX
02 / VOLUMETRIC ANALYSIS
From whole matrix
to spatial phenotype.
Measure the complete capture volume, then reconstruct individual traps as registered three-dimensional objects for event-level biological analysis.
01
Whole-matrix context
Measure the complete capture volume before selecting an individual event.
01 / WHOLE MATRIXSELECT ONE REGISTERED EVENT↓
02 / 3D SPATIAL PHENOTYPE03 / STRUCTURE-CENTRIC OUTPUTS
What the platform
turns into data.
The output is not a single fluorescence value. Each measurement retains its relationship to the complete matrix and the original three-dimensional event.
Population burden
Count, area fraction and distribution across the complete capture matrix.
Trap morphology
Size, branching, compactness, porosity, aggregation and structural class.
Marker localization
Spatial overlap of study-selected molecular signals within a preserved event.
Cell relationships
Cells within, contacting or adjacent to the extracellular trap volume.